Development of Anti-diabetic Niosomes Formulation Containing Metformin and Gliclazide
نویسندگان
چکیده
منابع مشابه
Formulation of Insulin Containing Niosomes and the Effect of Their Oral Administration on Blood Glucose in Streptozotocin-induced Diabetic rats
Multilamellar vesicles (noisome) of polyoxyethylene alkyl ether surfactants (Brij 52, 72, 76 and 92) were prepared using classic film hydration method. Vesicle formation ability of the surfactants was assessed in presence or absence of cholesterol. All used surfactants formed vesicles in the absence of cholesterol. Recombinant human insulin was used as a model protein drug to investigate encaps...
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Span 20-based niosome was prepared by lipid film hydration technique and loaded with Newcastle disease vaccine. Three batches with Span 20, cholesterol and dicetyl phosphate in micro molar ratios of 10:10:1; 15:15:1 and 20:20:1 were prepared and evaluated for encapsulation efficiency using haemagglutination test. The morphology of the vesicles was studied by means of transmission electron micro...
متن کاملFormulation and Evaluation of In-vitro Characterization of Gastic-Mucoadhesive Microparticles/Discs Containing Metformin Hydrochloride
The present study involves preparation and evaluation of gastric-mucoadhesive microparticles with Metformin Hydrochloride as model drug for prolongation of gastric residence time. The microparticles were prepared by the emulsification solvent evaporation technique using polymers of Carbomer 934p (C) and Ethylcellulose (EC). The microparticles were prepared by emulsion solvent evaporation method...
متن کاملFormulation and Evaluation of In-vitro Characterization of Gastic-Mucoadhesive Microparticles/Discs Containing Metformin Hydrochloride
The present study involves preparation and evaluation of gastric-mucoadhesive microparticles with Metformin Hydrochloride as model drug for prolongation of gastric residence time. The microparticles were prepared by the emulsification solvent evaporation technique using polymers of Carbomer 934p (C) and Ethylcellulose (EC). The microparticles were prepared by emulsion solvent evaporation method...
متن کاملDevelopment And Validation Of A Hplc Method For The Determination Of Metformin Hydrochloride, Gliclazide And Piogliglitazone Hydrochloride In Multicomponent Formulation
A simple, rapid, and precise reversed-phase high-performance liquid chromatographic method for simultaneous analysis of metformin hydrochloride, gliclazide, and pioglitazone hydrochloride in a tablet dosage form has been developed and validated. Chromatography was performed on a 25 cm × 4.6 mm i.d., 5-μm particle, C18 column with 85:15 (v/v) methanol: 20 mM potassium dihydrogen phosphate buffer...
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ژورنال
عنوان ژورنال: Indian Journal of Pharmaceutical and Biological Research
سال: 2017
ISSN: 2320-9267
DOI: 10.30750/ijpbr.5.2.5